Dieta mediterrânea para prevenção de doenças cardiovasculares: overview de revisões sistemáticas / Mediterranean diet for prevention of cardiovascular diseases: overview of systematic reviews

Contextualização: As doenças cardiovasculares (DCV) representam a principal causa de morte no Brasil e no mundo e a dieta mediterrânea (DM) surgiu como possibilidade de prevenção dessas doenças. Ela envolve o alto consumo de frutas, vegetais, frutos do mar, nozes, legumes, grãos e azeite, e ingestão moderada de vinho nas refeições, além de menor ingestão de carnes vermelhas e processadas, gordura saturada, doces e bebidas açucaradas. Objetivo: Avaliar a efetividade da DM para prevenção de DCV. Métodos: Trata-se de overview de revisões sistemáticas. Procedeu-se à busca por estudos que associavam a DM às DCV em quatro bases eletrônicas de dados: Cochrane - Central de Registros de Ensaios Clínicos - CENTRAL (2023), PubMed (1966-2023), Portal BVS (1982-2023) e EMBASE (1974-2023). Dois pesquisadores, independentemente extraíram os dados e avaliaram a qualidade dos estudos para a síntese. O desfecho primário de análise envolveu a prevenção de doença cardiovascular e a redução de mortalidade. Resultados: 5 revisões sistemáticas foram incluídas, totalizando 74 ensaios clínicos (n = 124.820) e 16 coortes prospectivas (n = 722.495). Discussão: Embora os estudos incluídos relatem benefícios favoráveis à DM para prevenção de DCV, as evidências são de baixa a moderada qualidade, diante da heterogeneidade e fragilidades metodológicas. Sugere-se a realização de novos estudos clínicos com padronização de relato dos resultados. Conclusão: Parece haver benefício da DM para prevenção de DCV, mas diante das evidências limitadas, há incertezas que tornam lícita a recomendação por novos ensaios clínicos com comparação a outras dietas, para maior robustez dos achados.

Índice de Dieta Mediterránea y pH Salival en Mujeres Adultas. Estudio Observacional / Mediterranean Diet Index and Salivary pH in Adult Women. Observational Study

El ser humano en el transcurso de la evolución ha cambiado la percepción de la alimentación dejando de lado el consumo de carne y sus derivados por factores éticos y morales, donde se sabe la dieta tiene gran relevancia en la salud general, siendo un factor de riesgo para la aparición de diversas enfermedades motivo por cual la saliva se ha utilizado como instrumento de diagnóstico Describir y comparar el índice de Dieta mediterránea según pH salival en mujeres estudiantes de Odontología de entre 20 a 30 años. Estudio descriptivo transversal comparativo. Participaron 17 mujeres adultas seleccionadas por criterio no probabilístico en la carrera de Odontología, quienes fueron evaluadas en su índice de Dieta mediterránea y pH salival. Se aplicó la prueba T de Student para muestras independientes y U Mann-Whitney para comparar características entre grupos en función del pH salival. Existen diferencias significativas entre grupos para la frecuencia de consumo de cereales integrales (p = 0,026), carnes magras (p = 0,021) y pH salival (p < 0,001). Existe un predominio hacia la baja adherencia a una dieta mediterránea, existiendo diferencias significativas en la frecuencia de consumo de cereales integrales y carnes magras, siendo el consumo de estos un indicador del riesgo de la cavidad oral determinado por pH.

The human being in the course of evolution has changed the perception of food, leaving aside the consumption of meat and its derivatives due to ethical and moral factors, where it is known that diet has great relevance in general health, being a factor of risk for the appearance of various diseases, which is why saliva has been used as a diagnostic tool. To describe and compare the Mediterranean Diet index according to salivary pH in female dentistry students between 20 and 30 years old. Comparative cross-sectional descriptive study. Seventeen adult women selected by non-probabilistic criteria participated in the Dentistry career, who were evaluated in their Mediterranean Diet index and salivary pH. Student's T test for independent samples and Mann-Whitney U test were applied to compare characteristics between groups based on salivary pH. There are significant differences between groups for the frequency of consumption of whole grains (p = 0.026), lean meats (p = 0.021) and salivary pH (p < 0.001). There is a predominance towards low adherence to a Mediterranean diet, with significant differences in the frequency of consumption of whole grains and lean meats, the consumption of these being an indicator of oral risk determined by pH.

Modification of Mediterranean Diet Pyramid from an Island's perspective / Alteração da Pirâmide Alimentar Mediterrânea na perspectiva de uma Ilha

ABSTRACT Objective The present study aimed to determine traditional and local food consumption and adherence to the Mediterranean diet in Cyprus. And also, aimed to improve their adherence to the Mediterranean diet and traditional and local food consumption. From this point, this current study aimed to revise the Cyprus Mediterranean Diet Pyramid, based on the Current Mediterranean Diet Pyramid. Methods The sample size was calculated as a minimum of 386 according to a 95.0% confidence interval, and a 5.0% error. This study was conducted online between November 2020-April 2021 in Cyprus. All volunteers were invited to this study on the national public internet platforms. Participant´s adherence to the Mediterranean diet was determined by the Mediterranean Diet Adherence Screener. Traditional and local food consumption frequencies were determined by a Food Frequency Questionnaire. A novel Cyprus Mediterranean Diet Pyramid was developed with traditional and local food items for Cyprus. The modification was also aimed to safeguard planet health, to increase traditional food consumption and adherence to the Mediterranean diet. Results 1,007 adults (78.0% native islanders/Cypriots) participated voluntarily in the current study. The mean Mediterranean Diet Adherence Screener score was 7.55±2.30 points and only 34.4% had high adherence to the Mediterranean diet. According to their responses, there was a need to increase use of olive oil, vegetables, fruits, fish, and red wine consumption and to decrease red meat and dessert consumption. According to responses to the Mediterranean Diet Adherence Screener and their traditional/local food consumption frequencies an up-to-date Cyprus Mediterranean Diet Pyramid was done hence a national food pyramid for Cyprus. Commonly consumed traditional and local foods were added to the pyramid to facilitate increased adaptation of the Mediterranean diet in the general population. Adequately consumed foods were added to make it more region-specific and rarely consumed foods were added to help to increase consumption. Conclusion This modification is believed to be instrumental to increase Mediterranean diet adaptation, traditional/local food consumption and decrease the impact of nutrition on the planet´s health. And also, this modification can shed light on the development of the other traditional food pyramids.

RESUMO Objetivo Este estudo teve como objetivo determinar o consumo alimentar tradicional e local, bem como a adesão à dieta mediterrânea no Chipre. Também teve como objetivo melhorar a adesão à dieta mediterrânea e ao consumo de alimentos tradicionais e locais. A partir desse ponto, este trabalho atual teve como objetivo revisar a Pirâmide da Dieta Mediterrânea do Chipre, que é baseada na Pirâmide da Dieta Mediterrânea Atual. Métodos O tamanho da amostra foi calculado com um mínimo de 386 de acordo com intervalo de confiança de 95,0% e erro de 5,0%. Este estudo foi realizado online entre novembro de 2020 e abril de 2021 em Chipre. Todos os voluntários foram convidados para esta análise nas plataformas públicas nacionais de internet. A adesão dos participantes à dieta mediterrânea foi avaliada pelo Medidor de Adesão à Dieta Mediterrânea. As frequências de consumo alimentar tradicional e local foram determinadas pelo Questionário de Frequência Alimentar. Foi desenvolvida uma nova Pirâmide da Dieta Mediterrânica de e para o Chipre, com alimentos tradicionais e locais. A modificação teve também como objetivo salvaguardar a saúde do planeta, aumentar o consumo de alimentos tradicionais e a adesão à dieta mediterrânea. Resultados No total de 1.007 adultos (78,0% naturais da ilha/cipriotas) participaram voluntariamente no estudo. A pontuação média obtida no Medidor de Adesão à Dieta Mediterrânea foi de 7,55±2,30 pontos, com apenas 34,4% aderindo fortemente à dieta mediterrânea. De acordo com as suas respostas, houve necessidade de aumentar a utilização de azeite, vegetais, frutas, peixe e vinho tinto, bem como de diminuir o consumo de carnes vermelhas e sobremesas. Com base nas suas respostas ao Medidor de Adesão à Dieta Mediterrânea e as suas frequências de consumo alimentar tradicional/local, foi feita uma pirâmide da Dieta Mediterrânea do Chipre atualizada, ou seja, uma pirâmide alimentar nacional para o Chipre. Alimentos locais e regionais comumente consumidos foram adicionados à pirâmide para aumentar a adesão à dieta mediterrânea. Alimentos consumidos de acordo com as recomendações foram adicionados para torná-los específico da região, e alimentos pouco consumidos foram adicionados para ajudar a aumentar o consumo. Conclusão Acredita-se que esta modificação seja determinante para aumentar a adaptação da dieta mediterrânea e o consumo de alimentos tradicionais e locais, além de diminuir o impacto da nutrição na saúde do planeta. Ainda, essa modificação pode lançar luz sobre o desenvolvimento das outras pirâmides alimentares tradicionais.

Cardiometabolic risk profile in relation to the practice of healthy habits in a sample of Spanish workers

Insulin resistance is a pathological entity that can lead to alterations in lipid metabolism and can increase cardiovascular risk. Objective. The aim of this study was to assess the influence of different sociodemographic variables such as age, sex and social class and healthy habits such as smoking, physical activity and adherence to the Mediterranean diet on the cardiometabolic profile of Spanish workers. Material and methods. A descriptive, cross-sectional study was carried out in 1457 Spanish workers in an attempt to evaluate the effect of healthy habits (physical exercise determined with the IPAQ questionnaire, Mediterranean diet and tobacco consumption) and sociodemographic variables (age, sex and social class) on the values of different insulin resistance scales. Results. The progressive increase in the level of physical activity and high adherence to the Mediterranean diet achieved an improvement in the mean values and in the prevalence of elevated values in all the insulin resistance scales analyzed in this study. Age over 50 years and belonging to the least favored social classes (social classes II-III) were the variables that increased the risk of presenting insulin resistance. Male sex also increased the risk of presenting insulin resistance. Conclusions. The different healthy habits such as vigorous physical exercise and high adherence to the Mediterranean diet improve the values of the different scales that assess insulin resistance(AU)

La resistencia a la insulina es una entidad patológica que puede provocar alteraciones en el metabolismo de los lípidos y puede aumentar el riesgo cardiovascular. Objetivo. En este trabajo se pretende valorar la influencia de diferentes variables sociodemográficas como la edad, el sexo y la clase social y hábitos saludables como el consumo de tabaco, la actividad física y la adherencia a la dieta mediterránea en el perfil cardiometabólico de trabajadores españoles. Material y métodos. Se realizó un estudio descriptivo y transversal en 1457 trabajadores españoles intentando evaluar el efecto de los hábitos saludables (ejercicio físico determinado con el cuestionario IPAQ, dieta mediterránea y consumo de tabaco) y las variables sociodemográficas (edad, sexo y clase social) sobre los valores de diferentes escalas de resistencia a la insulina. Resultados. El aumento progresivo del nivel de actividad física y la alta adherencia a la dieta mediterránea consiguieron una mejoría en los valores medios y en la prevalencia de los valores elevados en todas las escalas de resistencia a la insulina analizadas en este estudio. La edad por encima de los 50 años y la pertenencia a las clases sociales menos favorecidas (clases sociales II-III) fueron las variables que aumentaron el riesgo de presentar resistencia a la insulina. El sexo masculino también incrementó el riesgo de presentar resistencia a la insulina. Conclusiones. Los diferentes hábitos saludables como el ejercicio físico vigoroso y la alta adherencia a la dieta mediterránea mejoran los valores de las diferentes escalas que valoran resistencia a la insulina(AU)

Factores bioquímicos asociados a la adherencia a la dieta mediterránea / Biochemical factors associated with adherence to a Mediterranean Diet

Introducción: Existen evidencias respecto a la relación inversa, entre la adherencia a la dieta mediterránea y el desarrollo de padecimientos crónicos como enfermedad coronaria, síndrome metabólico y diabetes. Objetivo: Determinar los factores bioquímicos asociados a la adherencia a la dieta mediterránea, en pacientes atendidos en un centro médico peruano. Métodos: Estudio transversal en 209 pacientes atendidos en un centro médico de Lima, Perú. Se utilizó el cuestionario PREDIMED para medir la adherencia a la dieta mediterránea. Se indagó la correlación entre el puntaje de adherencia a la dieta mediterránea y las covariables, edad, sexo, hipertrigliceridemia, hipercolesterolemia, hiperglicemia en ayunas y diagnóstico nutricional. Se utilizaron modelos lineales generales. Resultados: De 209 participantes, la mayoría fueron hombres (79,9 por ciento) y la mediana de edad fue de 31 años. El 20,2 por ciento tenía obesidad, quienes presentaron alteraciones en triglicéridos, fueron el 29,1 por ciento, colesterol (21,7 por ciento) y glicemia en ayunas (26,8 por ciento). En cuanto al puntaje del PREDIMED, la media fue de 4,6 puntos. Se encontró que la hiperglicemia en ayunas (Coef. = -2,08) tuvo asociación negativa con el puntaje de adherencia a la dieta mediterránea. Conclusión: La adherencia al patrón de dieta mediterránea es baja, y se correlaciona de forma negativa con hallazgos de hiperglicemia en los participantes evaluados (AU)

Introduction: There is evidence regarding the inverse relationship between adherence to the Mediterranean diet and the development of chronic conditions such as coronary heart disease, metabolic syndrome and diabetes. Objective: To determine the factors associated with adherence to the Mediterranean diet in patients attended in a Peruvian medical center. Methods: Cross-sectional analytical study in 209 patients attended at a medical center in Lima, Peru. The PREDIMED questionnaire was used to measure adherence to Mediterranean diet. Correlation between the Mediterranean diet adherence score and the covariates, age, sex, hypertriglyceridemia, hypercholesterolemia, fasting hyperglycemia and nutritional diagnosis was investigated. General linear models were used. Results: Of 209 participants, the majority were male (79.9 %) and the median age was 31 years. The 20.2 percent had obesity, those who presented alterations in triglycerides were 29.1 percent, cholesterol (21.7 percent) and fasting glycemia (26.8 percent). As for the PREDIMED score, the mean was 4.6 points. It was found that fasting hyperglycemia (Coef. = -2.08) had a negative association with the Mediterranean diet adherence score. Conclusion: Adherence to the Mediterranean diet pattern is low, and is negatively correlated with hyperglycemia findings in the participants evaluated(AU)

Adherencia a la dieta mediterránea en niños y adolescentes deportistas: revisión sistemática / Adherence to the mediterranean diet in child and adolescent athletes: a systematic review

Resumen Peláez Barrios, E.M. y Vernetta Santana M. (2021). Adherencia a la dieta mediterránea en niños y adolescentes deportistas: revisión sistemática. PENSAR EN MOVIMIENTO: Revista de Ciencias del Ejercicio y la Salud, 19(1), 1-19. El objetivo de esta revisión fue analizar los estudios realizados en niños y adolescentes deportistas que utilizaban el índice KIDMED para conocer la adherencia a la dieta mediterránea (ADM). Se realizó una búsqueda en diferentes bases de datos: WOS, Scopus, Google Scholar, Pubmed y Sport Discuss, entre el 1 de enero de 2010 y el 1 de junio de 2020, siguiendo la guía PRISMA. De los 82 estudios identificados, 10 analizaron la ADM y cumplieron con todos los criterios de inclusión. Los resultados obtenidos indicaron que los mayores porcentajes de ADM óptima se evidencian en piragüistas masculinos, seguidos de futbolistas masculinos, gimnastas de rítmica y kayakistas femeninas (66%, 54.8%, 52.2% y 51%, respectivamente). En todos los deportistas analizados, los resultados son mejorables, principalmente en el caso de las jugadoras de futbol sala. En la mayoría de los estudios no existe una relación entre ADM y las medidas antropométricas. Como conclusión, se destaca que la mayoría de los deportistas se encuentran entre una mejorable y óptima adherencia a la dieta mediterránea y son pocos los que obtienen porcentajes bajos de adherencia a la dieta mediterránea; destaca un patrón de adherencia a la dieta mediterránea aceptable casi en su totalidad, pero no óptimo. Además, la mayoría de los estudios incluidos en la revisión sistemática obtienen una alta calidad según las directrices STROBE.

Abstract Peláez Barrios, E.M. & Vernetta Santana M. (2021). Adherence to the mediterranean diet in child and adolescent athletes: a systematic review. PENSAR EN MOVIMIENTO: Revista de Ciencias del Ejercicio y la Salud, 19(1), 1-19. The objective of this review was to analyze studies conducted in child and adolescent athletes using the KIDMED index to study their adherence to the Mediterranean diet (ADM). A search was conducted in different databases including WOS, Scopus, Google Scholar, PubMed, and Sport Discuss between January 1st and June 1st, 2020, following the PRISMA guide. Of the 82 studies identified, 10 articles analyzed ADM and met all the inclusion criteria. Results indicated that the highest percentages of optimal ADM are evident in male canoeists, followed by male soccer players, rhythmic gymnasts, and female kayakers (66%, 54.8%, 52.2%, and 51%, respectively). Results are improvable in all the athletes analyzed, mainly in female futsal players. Most studies do not show a relationship between ADM and anthropometric measurements. In conclusion, most athletes show between improvable and optimal adherence to the Mediterranean diet, and only a few obtain low adherence percentages. Therefore, the pattern of adherence to the Mediterranean diet is mostly acceptable but not optimal. In addition, the quality of most of the studies included in the systematic review are rated high based on the STROBE guidelines.

Resumo Peláez Barrios, E.M. e Vernetta Santana M. (2021). A adesão à dieta mediterrânea em crianças e adolescentes esportistas: revisão sistemática. PENSAR EN MOVIMIENTO: Revista de Ciencias del Ejercicio y la Salud, 19(1), 1-19. Esta revisão teve como objetivo analisar os estudos realizados em crianças e adolescentes esportistas que utilizavam o índice KIDMED para entender a adesão à dieta mediterrânea (ADM). Foi realizada uma busca em diferentes bases de dados: WOS, Scopus, Google Scholar, Pubmed e Sport Discuss, entre 1º de janeiro de 2010 e 1º de junho de 2020, seguindo a recomendação PRISMA. Dos 82 estudos identificados, 10 analisaram a ADM e cumpriram todos os critérios de adesão. Os resultados obtidos indicaram que as maiores porcentagens de ADM ideal se evidenciaram em canoístas masculinos, seguidos de futebolistas masculinos, ginastas rítmicas masculinos e canoístas femininas (66%, 54,8%, 52,2% e 51%, respectivamente). Em todos os esportistas analisados, os resultados são aperfeiçoáveis, principalmente no caso das jogadoras de futebol de salão. Na maioria dos estudos não existe uma relação entre ADM e as medidas antropométricas. Em conclusão, destaca-se que a maioria dos esportistas estão entre uma aperfeiçoável e ótima adesão à dieta mediterrânea e são poucos os que obtém baixas porcentagens de adesão a ela; destaca-se um padrão de adesão à dieta mediterrânea aceitável praticamente total, mas não ótimo. Além disso, a maioria dos estudos incluídos na revisão sistemática obtém uma alta qualidade de acordo com as diretrizes STROBE.

Adherence to the mediterranean diet in elementary school children (1st cycle) / Adesão à dieta mediterrânica em crianças do 1º ciclo de escolaridade

ABSTRACT Objective: To characterize the adherence to the Mediterranean diet (MD) in students from elementary schools in Porto and Maia and analyze its association with sleep hygiene, physical activity, cardiometabolic risk, and school performance. Methods: This is a cross-sectional study with 891 Portuguese students: 455 boys (51%) and 436 girls (49%), aged between 9 and 11 years old (mean [M]=9.2, standard deviation [SD]=0.4), with an average weight of 35.9 kg (SD=8.1), average height of 1.4 m (SD=0.1), average body mass index (standardized BMI Z score for the pediatric age group) of 0.76 (SD=1.21); 59.5% of them had normal weight and 15.9% were obese. The students filled a questionnaire on the adherence to the Mediterranean Diet (Mediterranean Diet Quality Index in Children and Adolescents [KIDMED]), participated in a socio-demographic interview, and had their anthropometric data collected after their parents signed the informed consent form. Results: The results suggest high levels of adherence to the MD (77.6%) both in males and females. Using Pearson's correlation coefficient, we found that the Z score was positively associated to cardiometabolic risk and the starting age of an extracurricular physical activity, and negatively associated to the average hours of sleep on a typical day both in males and females. We also identified a negative relation between KIDMED and the starting age of physical activity. Conclusions: This study has contributed to the knowledge of adherence to the MD among Portuguese elementary students and correlations with variables associated to a healthier lifestyle (MD, hours of sleep, and physical activity). Future studies should focus their attention on other countries and more heterogeneous samples.

RESUMO Objetivo: Caracterizar a adesão à dieta mediterrânica de alunos de escolas primárias do Porto e Maia e analisar a sua associação com a higiene do sono, a atividade física, o risco cardiometabólico e o desempenho escolar. Métodos: Estudo transversal com 891 alunos portugueses: 455 meninos (51%) e 436 meninas (49%), entre 9 e 11 anos (média [M]= 9,2; desvio padrão [DP]= 0,4), peso médio 35,9 kg (DP= 8,1), estatura média 1,4 cm (DP= 0,1), índice de massa corporal médio (IMC padronizado por escore Z para a faixa etária pediátrica) 0,76 (DP= 1,2), 59,5% de pessoas com peso adequado e 15,9% de obesos. Os alunos completaram o Índice de Qualidade de Adesão à Dieta Mediterrânica em Crianças e Adolescentes (Mediterranean Diet Quality Index in Children and Adolescents [KIDMED]) e uma entrevista sociodemográfica e dados antropométricos, após obtenção do consentimento informado dos pais. Resultados: Os resultados sugerem altos níveis de adesão ao padrão alimentar mediterrânico (77,6%), tanto nos meninos como nas meninas. Recorrendo ao coeficiente de correlação de Pearson, encontramos associação positiva entre o escore Z e o risco cardiometabólico, associação negativa entre o escore Z e a média de horas de sono em um dia típico nos meninos e nas meninas, associação positiva entre o escore Z e a idade de início de uma atividade física extracurricular e associação negativa entre o KIDMED e a idade de início da atividade física. Conclusões: Este estudo contribuiu para o conhecimento da adesão ao padrão alimentar mediterrânico de alunos do 1º ciclo de escolaridade do Porto e da Maia e correlações com variáveis associadas a um estilo de vida mais saudável (adesão à dieta mediterrânica, horas de sono e atividade física). Estudos futuros deverão focar a sua atenção em outros países e com amostras mais heterogêneas.

Nivel de ansiedad según el tipo de desayuno en escolares durante el estado de alarma por la COVID-19 en España / Anxiety level and breakfast type in schoolchildren during the COVID-19 state of alarm in Spain

Introducción: El desayuno suscita un considerable interés científico como posible parámetro relacionado con el estilo de vida. Objetivo: Analizar los niveles de ansiedad según el tipo de desayuno en escolares de Educación Primaria durante el estado de alarma decretado en España a causa de la COVID-19. Métodos: Estudio transversal compuesto por 116 escolares de la Isla de Fuerteventura. Se valoró la ansiedad a través del cuestionario Spence Children Anxiety Scale (SCAS). Los ítems referidos al desayuno fueron extraídos del test de Adhesión a la Dieta Mediterránea KIDMED. Las pruebas estadísticas utilizadas fueron el análisis de varianza simple (one way ANOVA) y la prueba de regresión logística multivariante. Resultados: La ingesta de un cereal se asocia con una menor probabilidad de desarrollar ataques de pánico y agorafobia (OR = 1,14, p < 0,01), fobia social (OR = 0,71, p < 0,05), trastorno obsesivo-compulsivo (OR = 1,22, p < 0,05) e índice ansiedad global (OR = 1,05, p < 0,05). Asimismo, no desayunar bollería habitualmente se asoció con una menor probabilidad de desarrollar un trastorno obsesivo-compulsivo (OR = 1,13; p < 0,05). Conclusiones: Una calidad del desayuno óptima, como consumir cereales saludables y no consumir bollería industrial, se asocia con menores niveles de ansiedad en escolares de Educación Primaria durante el estado de alarma decretado en España a causa de la COVID-19(AU)

Introduction: Breakfast arouses considerable scientific interest as a potential lifestyle parameter. Objective: Analyze the relationship between anxiety levels and breakfast type in schoolchildren. Methods: A cross-sectional study was conducted of 116 schoolchildren from the Isle of Fuerteventura. Anxiety was evaluated with the Spence Children Anxiety Scale (SCAS) questionnaire. Items about breakfast were taken from the KIDMED Test of Adherence to the Mediterranean Diet. Statistical processing was based on one way ANOVA and the multivariate logistic regression test. Results: Intake of a cereal is associated to a lesser probability of developing agoraphobia and panic attacks (OR = 1.14, p < 0.01), social phobia (OR = 0.71, p < 0.05), obsessive-compulsive disorder (OR = 1.22, p < 0.05) and overall anxiety index (OR = 1.05, p < 0.05). On the other hand, not having pastry for breakfast habitually was associated to a lesser probability of developing obsessive-compulsive disorder (OR = 1.13; p < 0.05). Conclusions: Optimum breakfast quality, such as eating healthy cereals and not eating industrial pastries, is associated to lower levels of anxiety in schoolchildren during the state of alarm decreed in Spain due to the COVID-19 pandemic(AU)

Intestinal Microbiota and Cardiovascular Diseases

Abstract Recently, gut microbiota has emerged as an important mediator of several diseases such as diabetes, atherosclerosis, arterial hypertension, obesity, cancers and neuropsychiatric diseases including Alzheimer, autism and depression. Intestinal microbiota is formed by bacteria, fungi and viruses and its main function is to facilitate the absorption and metabolism of foods (protein, fat and carbohydrate). One example of the multiple actions of the gut microbiota is the bidirectional relationship between the intestine and the brain, the so-called "gut/brain axis". Furthermore, metabolites produced by gut microbiota can induce effects locally or at distance, which suggests that the intestine is an endocrine organ. Given the participation of the gut microbiota in several diseases, there is great interest in strategies that may positively affect the gut flora and prevent or even treat diseases. Among these strategies, lifestyle change, but specially diet modulation has gained importance. In this article, we review the mechanisms through which intestinal microbiota participates in cardiovascular diseases and possible therapeutic interventions.

Migración de neutrófilos en larvas de pez cebra expuestos a extractos de sofrito de tomate / Neutrophils migration in zebrafish larvae exposed to tomato sofrito extracts

Este trabajo se fundamenta en la evaluación de la actividad antiinflamatoria de extractos de sofrito de tomate, así como de compuestos estándares de la dieta mediterránea, usando un modelo experimental optimizado basado en larvas de pez cebra. La migración de neutrófilos en larvas de pez cebra de 96 horas post fertilización se indujo mediante una lesión y se potenció añadiéndole lipopolisacárido, dicha migración se visualizó y cuantificó mediante análisis de imagen. El efecto antiinflamatorio del extracto de tomate y de los compuestos utilizados fue correlacionado porcentualmente por la disminución de la migración de los neutrófilos. Los resultados muestran que el extracto de tomate presentó una reducción en la migración de neutrófilos de 40 % respecto al grupo control. Por otra parte, el ácido clorogénico y la cianidina presentes en el sofrito de tomate utilizados como estándares presentaron una disminución de la migración de neutrófilos de un 66,7 % y 62,5 % respectivamente. Estos porcentajes son comparables a los resultados observados en ensayos con drogas antiinflamatorias como la indometacina y piroxicam. Los resultados muestran que el extracto de sofrito de tomate presenta posible actividad antinflamatoria demostrada por la reducción de la migración de neutrófilos, además el modelo se mostró sensible y válido para ser aplicado en matrices alimentarias complejas(AU)

The main of this study was to evaluate the anti-inflammatory activity of tomato sofrito extracts, as well as standard compounds present in the Mediterranean diet, using an optimized experimental model based on zebrafish larvae. Neutrophil migration in zebrafish larvae 96 hours post fertilization was induced by a cut in the caudal fin and enhanced by adding lipopolysaccharide and was visualized and quantified by image analysis. The anti-inflammatory effect of tomato extract and the compounds used was correlated by the percentage decrease in the migration of neutrophils. The results showed that, tomato extract showed a reduction in neutrophil migration of 40% compared to the control group. Moreover, chlorogenic acid and cyanidin present in tomato sofrito sauce showed a decrease in neutrophil migration of 66.7% and 62.5% respectively. These percentages are comparable to the results observed in trials with anti-inflammatory drugs such as indomethacin and piroxicam. The results show that tomato sofrito extract has possible anti-inflammatory activity demonstrated by the reduction of neutrophil migration, furthermore the model was sensitive and valid to be applied in complex food matrices(AU)

Nutritional genomics, inflammation and obesity

ABSTRACT The Human Genome Project has significantly broadened our understanding of the molecular aspects regulating the homeostasis and the pathophysiology of different clinical conditions. Consequently, the field of nutrition has been strongly influenced by such improvements in knowledge - especially for determining how nutrients act at the molecular level in different conditions, such as obesity, type 2 diabetes, cardiovascular disease, and cancer. In this manner, characterizing how the genome influences the diet and vice-versa provides insights about the molecular mechanisms involved in chronic inflammation-related diseases. Therefore, the present review aims to discuss the potential application of Nutritional Genomics to modulate obesity-related inflammatory responses. Arch Endocrinol Metab. 2020;64(3):205-22

Dieta mediterránea: modelo de alimentación para contribuir a la salud humana y del planeta / Mediterranean diet: food model to contribute to human and planet health

Una dieta saludable y sostenible provee los requerimientos nutricionales para la salud del ser humano y que además es saludable para nuestro planeta. Objetivo: resaltar la importancia de la dieta mediterránea como una dieta sostenible, destacando su efecto positivo para la salud humana y ambiental. Material y Métodos:la búsqueda de información se realizó en las bases de datos: PubMed/MEDLINE, SciELO, Elsevier, Cochrane, SpringerLink y Google Académico. La selección de información se centró en: 5 publicaciones de la Organización de las Naciones Unidas para la Alimentación y la Agricultura, de los últimos 7 años, 10 reportes del grupo de alto nivel de expertos en seguridad alimentaria y nutrición, mismos que iniciaron sus publicaciones en 2011, 29 artículos científicos y publicaciones del 2015 en adelante, en donde se realizó una excepción en cuanto a la antigüedad de dos publicaciones del 2009. Conclusión:la dieta mediterránea es una opción saludable para la salud, ya que disminuye la incidencia y probabilidad de ciertas enfermedades crónicas, contribuyendo también a una responsabilidad ambiental, al hacer uso eficiente de los recursos para la producción de los alimentos que formarán parte de esta dieta...(AU)

Factores de riesgo cardiovascular no convencionales / Unconventional cardiovascular risk factor

Desde hace varias décadas se conocen los clásicos factores de riesgo cardiovascular (género, edad, hipertensión arterial, dislipidemias, tabaquismo, obesidad, sedentarismo). También existen factores de riesgo "no convencionales", es decir situaciones no descriptas ni contenidas en la mayoría de los puntajes de riesgo tradicionales, pero de las cuales existen evidencias científicas. En esta revisión se analizan algunos de ellos, tales como factores socioeconómicos, horarios prolongados de trabajo, factores ambientales, aislamiento social, cantidad y calidad del sueño. También hay factores de "protección" cardiovascular como la dieta mediterránea. La literatura cuenta con un número muy elevado de publicaciones que abarcan estos factores. En la presente descripción se incluyeron algunas que fuesen representativas, con buen diseño experimental y que hayan realizado análisis multivariado de los resultados para controlar potenciales confundidores que invaliden las conclusiones. Finalmente, se discuten los mecanismos fisiopatológicos involucrados en la generación de los eventos cardiovasculares finales. (AU)

The classical cardiovascular risk factors have been known for several decades (gender, age, arterial hypertension, dyslipidemia, smoking, obesity, sedentary lifestyle). There also exist "non conventional" risk factors, that are those not described or not included in the majority of the traditional cardiovascular risk scores, but for whom scientific evidence is available. In this review some of them are analyzed, such as socio economic factors, prolonged work schedules, environmental factors, social isolation, sleep quantity and quality. There are also some "preventive" cardiovascular factors as the Mediterranean diet. There exist considerable amount of publications in the literature analyzing these issues. In the present paper some of them are discussed. They have been selected as they were representative of the corresponding aspect, well designed and with multivariate statistical analysis of the results, in order to control potential confounders that could invalidate the conclusions. Finally, the pathophysiological mechanisms involved are discussed. (AU)

Weight loss-what's the most effective diet type?: a scoping review / Pérdida de peso-¿cuál es el tipo de dieta más eficaz?: una revisión sistemática exploratoria

OBJECTIVE: To evaluate which type of diet is most effective for weight loss. METHODS: Relevant studies for this type of review were identified from March to May 2018 by several sources, in the electronic databases PubMed, CINAHL, Scielo, SCOPUS, Web of Science, BVS Portal, EMBASE and Cochrane Library. For gray literature, Open Green and Base search and hand search repositories, which is a free search for materials that address the subject were searched. RESULTS: The selected publications totaled 537, of which 104 were from the electronic databases and 433 records identified through other databases. After the removal of duplicates, 113 titles and abstracts and 37 complete texts were selected, after reading the articles in full, 14 articles were selected for inclusion in this review. Out of the 14 articles analyzed, relevant results were presented for a diet rich in fruits and vegetables; oleaginous, especially nuts; a Mediterranean diet was noted in three studies; dietary guidelines based on guides was mentioned in two studies and a high-protein diet was cited four times. CONCLUSION: The most effective diet for weight loss was the high fiber diet, although it contributes with small percentage value.

OBJETIVO: evaluar qué tipo de dieta es la más efectiva para perder peso. MÉTODOS: los estudios relevantes para este tipo de revisión fueron identificados de marzo a mayo de 2018 por varias fuentes, en las bases de datos electrónicas PubMed, CINAHL, Scielo, SCOPUS, Web of Science, BVS Portal, EMBASE y Cochrane Library en la literatura gris Open Creen y Base de búsqueda y repositorios de búsqueda manual, que es una búsqueda gratuita de materiales que tratan el tema. RESULTADOS: Las publicaciones seleccionadas totalizaron 537, de las cuales 104 eran de las bases de datos electrónicas y 433 registros identificados a través de otras bases de datos. Después de la eliminación de los artículos duplicados, se seleccionaron 113 títulos y resúmenes y 37 textos completos; después de leer los artículos completos, se seleccionaron 14 artículos para su inclusión en esta revisión. De los 14 artículos analizados se presentaron resultados relevantes para una dieta rica en frutas y verduras; oleaginoso, especialmente los frutos secos; Dieta mediterránea en tres estudios; Pautas dietéticas basadas en guías dietéticas, presentes en dos estudios y dieta hiperproteica, citadas cuatro veces. CONCLUSIÓN: la dieta más efectiva para perder peso es la dieta alta en fibra, aunque contribuye con un pequeño valor porcentual.

Translation and cultural adaptation of the mediterranean diet quality index in children and adolescents / Tradução e adaptação cultural do mediterranean diet quality index in children and adolescents

ABSTRACT Objective: To translate and culturally adapt the Mediterranean Diet Quality Index in Children and Adolescent (KIDMED) for the Brazilian population. Methods: The processes of translation and cultural adaptation followed internationally standardized methodological norms. We used the intraclass correlation coefficient and the Bland-Altman dispersion analysis to assess the reproducibility and calculated the internal consistency with Cronbach's alpha coefficient. Results: A total of 102 children and adolescents participated in the cross-cultural adaptation, of whom 58 (56.9%) were females, with a mean age of 9.8±4.9 years. The mean overall scores of adherence to the Mediterranean diet in the test and retest were similar (8.00 and 3.80 versus 8.01 and 3.84) for children and adolescents, respectively. The intraclass correlation coefficient for children and adolescents was 0.893 and 0.998, respectively. The internal consistency was 0.72. The Bland-Altman plot analysis showed good agreement between the final scores of the test and retest questionnaires, with no statistically significant difference. Conclusions: The KIDMED questionnaire was translated into Brazilian Portuguese and culturally adapted, presenting high reproducibility. This questionnaire can, therefore, be included and used in Brazilian studies that aim at evaluating the adherence to the Mediterranean diet among children and adolescents.

RESUMO Objetivo: Traduzir e adaptar culturalmente a escala do Mediterranean Diet Quality Index in Children and Adolescent (KIDMED) para a população brasileira. Métodos: Os processos de tradução e adaptação cultural seguiram normas metodológicas padronizadas internacionalmente. A reprodutibilidade foi avaliada pelo coeficiente de correlação intraclasse e pela análise de dispersão de Bland-Altman, e a consistência interna foi calculada pelo coeficiente de Cronbach. Resultados: Participaram da etapa de adaptação transcultural 102 crianças e adolescentes, sendo 58 (56,9%) meninas com idade média de 9,8±4,9 anos. Os escores totais médio de aderência à dieta mediterrânea no teste e no reteste foram semelhantes (8,00 e 3,80 versus 8,01 e 3,84) para as crianças e os adolescentes, respectivamente. O coeficiente de correlação intraclasse para as crianças e os adolescentes foi de 0,893 e 0,998, respectivamente. A consistência interna obtida foi de 0,72. A análise do gráfico de Bland-Altman demonstrou boa concordância entre os escores finais dos questionários de teste e de reteste, sem diferença estatisticamente significativa. Conclusões: O questionário KIDMED foi traduzido e adaptado culturalmente para a língua portuguesa do Brasil, apresentando alta reprodutibilidade. Esse questionário pode ser, portanto, incluído e utilizado em estudos brasileiros que visem avaliar a aderência à dieta mediterrânea de crianças e adolescentes.

Association between adherence to the Mediterranean diet and the prevalence of cardiovascular risk factors / Associação entre adesão à dieta mediterrânea e prevalência de fatores de risco cardiovascular / Asociación entre la adherencia a la dieta mediterránea y la prevalencia de factores de riesgo cardiovascular

Objective: to determine the prevalence of cardiovascular risk factors in a cohort of workers and to quantify its association with compliance with the Mediterranean diet follow-up. Method: a cross-sectional descriptive study was carried out on a cohort of 23,729 workers. Clinical data from annual medical examinations and the Mediterranean Diet Adherence Screener were used to assess adherence to the Mediterranean diet. Results: 51.3% of the participants showed good adherence to the Mediterranean diet. The multivariate analysis showed an inverse and significant association between the follow-up of the Mediterranean diet and the prevalence of abdominal obesity (Odds Ratio = 0.64, 95% CI 0.56; 0.73), dyslipidemia (Odds Ratio = 0.55, 95% CI 0.42; 0.73), and metabolic syndrome (Odds Ratio = 0.76, 95% CI 0.67; 0.86). Conclusions: our results suggest that the Mediterranean diet is potentially effective in promoting cardiovascular health. Implementing the interventions promoting the Mediterranean diet in the working population seems justified.

Objetivo: determinar a prevalência de fatores de risco cardiovascular em uma coorte de trabalhadores e quantificar sua associação com o monitoramento da dieta mediterrânea. Método: estudo descritivo transversal, realizado em uma coorte de 23.729 trabalhadores. Dados clínicos dos exames médicos anuais e a Mediterranean Diet Adherence Screener foram usados para avaliar a adesão à dieta mediterrânea. Resultados: 51,3% dos participantes apresentaram boa adesão à dieta mediterrânea. A análise multivariada mostrou associação inversa e significativa entre o acompanhamento da dieta mediterrânea e a prevalência de obesidade abdominal (Odds Ratio = 0,64, IC 95% 0,56, 0,73), dislipidemia (Odds Ratio = 0,55, IC 95% 0,42, 0,73) e de síndrome metabólica (Odds Ratio = 0,76, IC 95% 0,67, 0,86). Conclusões: nossos resultados sugerem que a dieta mediterrânea é potencialmente eficaz na promoção da saúde cardiovascular. A implementação de intervenções que promovem a dieta mediterrânea na população trabalhadora parece justificada.

Objetivo: determinar la prevalencia de factores de riesgo cardiovascular en una cohorte de trabajadores y cuantificar su asociación con el seguimiento de la dieta mediterránea. Método: se llevó a cabo un estudio descriptivo transversal sobre una cohorte de 23.729 trabajadores. Se utilizaron los datos clínicos procedentes de los exámenes médicos anuales y el Mediterranean Diet Adherence Screener para evaluar la adherencia a la dieta mediterránea. Resultados: el 51,3% de los participantes presentó una buena adherencia a la dieta mediterránea. El análisis multivariante evidenció una asociación inversa y significativa entre el seguimiento de la dieta mediterránea y la prevalencia de obesidad abdominal (Odds Ratio = 0,64, IC 95% 0,56; 0,73), dislipidemia (Odds Ratio = 0,55, IC 95% 0,42; 0,73) y de síndrome metabólico (Odds Ratio = 0,76, IC 95% 0,67; 0,86). Conclusión: nuestros resultados sugieren que la dieta mediterránea es potencialmente eficaz en la promoción de la salud cardiovascular. Parece justificada la implementación de intervenciones que promuevan la dieta mediterránea en la población trabajadora.

Efectos de un programa alternativo de promoción de la alimentación saludable en comedor escolar / Effects of an alternative program to promote healthy eating in school canteen

Resumen El objetivo del estudio fue determinar los efectos sobre los hábitos alimentarios de escolares en una intervención educativa alternativa al modelo convencional de promoción de alimentación a un centro con comedor y proyecto de huerto ecológico. Estudio observacional descriptivo de corte transversal y comparativo de 111 niños y niñas entre 9 y 12 años, en el periodo 2013-15. Se comparó un colegio con intervención alternativa con otro que únicamente incluía contenidos propios del currículo de Educación Infantil y Primaria, mediante evaluación de adherencia a la dieta mediterránea del alumnado con cuestionario validado Kidmed. El centro de intervención presentó mayor adherencia a la dieta mediterránea que el centro control. En el centro de intervención el porcentaje de alumnado con dieta óptima (64,52%) fue mayor que los que necesitaban mejorar su dieta (33,87%), mientras que en el centro fue inferior (42,86% y 51,02% respectivamente). Los escolares del centro de intervención presentaron mayor porcentaje de respuestas afirmativas en ítems Kidmed. El programa de promoción de alimentación saludable alternativo del centro de intervención podría ser efectivo para la adquisición de una dieta de mayor adherencia a la dieta mediterránea.

Abstract The objective of this study was to determine the effects on school feeding habits in an educational intervention alternative to the conventional model of feeding promotion to a center with school canteens and ecological garden project. Cross-sectional and comparative descriptive observational study of 111 boys and girls between 9 and 12 years old, in the 2013-15 period. A school with alternative intervention was compared with another one that only included contents of the Infant and Primary Education curriculum, by means of evaluation of adherence to the mediterranean diet of the students with a validated Kidmed questionnaire. The intervention center presented greater adherence to the mediterranean diet than the control center. In the intervention center, the percentage of students with optimal diet (64.52%) was higher than those who needed to improve their diet (33.87%), contrary to what occurs in control center (42.86% and 51.02% respectively). The students of the intervention center presented a higher percentage of affirmative answers in Kidmed test. The program of promotion of healthy alternative food of the intervention center could be effective for the acquisition of a diet of greater adherence to the mediterranean diet.

Comidas tradicionales y alimentación saludable: el ejemplo de la dieta mediterránea / Traditional food and healthy diet: the Mediterranean diet example

La necesidad de tomar acciones que fortalezcan la promoción y prevención en salud ha permitido redescubrir a las comidas tradicionales como una opción para una alimentación saludable. Las comidas típicas permiten la convergencia de aspectos dietéticos y nutricionales, pero también de elementos sociales y culturales que se asocian a un plato culinario, lo que enriquece y da identidad a una persona, familias y comunidades. Esta revisión teoriza y reflexiona sobre la relación entre comidas tradicionales y alimentación saludable con base en uno de los patrones alimentarios más reconocido a nivel global, que es la dieta mediterránea. Esta forma de alimentación reúne a los alimentos y a las preparaciones culinarias saludables, incentiva un estilo de vida que previene la aparición de enfermedades crónicas y tiene una connotación sociocultural, que se basa en su denominación como patrimonio gastronómico de la humanidad, que da identidad a los países del Mediterráneo. El trabajo presenta las características de este patrón alimentario y su empleo clásico como dieta saludable. Así mismo, profundiza en su rol como parte del patrimonio cultural inmaterial de la humanidad, además de su empleo actual y su representación como alimentación saludable y sustentable, y plantea en la necesidad de reconocer a las comidas tradicionales como una oportunidad para la alimentación saludable.

The necessity for taking actions that strengthen activities intended for health promotion and disease prevention has allowed the rediscovery of traditional dishes as an option for healthy diet. Traditional dishes not only gather dietary and nutritional aspects, but also social and cultural elements associated with a culinary dish, all of which enrich and give identity to people, families and communities. This review theorizes and reflects on the relationship between traditional dishes and healthy diet based on one of the most well-known dietary patterns worldwide: the Mediterranean diet. This feeding regime allows the rendezvous between healthy food and culinary preparations, promotes a lifestyle that prevents the onset of chronic diseases, and has a sociocultural connotation based on its designation as culinary heritage of humanity, which gives identity to the Mediterranean nations. This article presents the characteristics of such feeding regime and its classic application as a healthy diet. It also goes more deeply into its role as part of the cultural intangible heritage of humanity, as well as its current application and representation as a healthy and sustainable diet, and poses the need for recognizing traditional dishes as an opportunity for healthy diet.

Análisis de la dieta mediterránea en escolares de Primaria, Secundaria y Bachillerato / Analysis of the Mediterranean diet in Primary, Secondary and high school students

RESUMEN La dieta Mediterránea es considerada uno de los modelos dietéticos más saludables. El objetivo es analizar el grado de adherencia a la dieta mediterránea (DM) en escolares atendiendo al sexo y etapa educativa. Se realizó un estudio descriptivo transversal (n= 634; 280 varones y 354 mujeres). La adherencia a la DM se halló a través del cuestionario KIDMED. La adherencia a la calidad de la DM no difiere significativamente entre varones y mujeres. Sin embargo, atendiendo por ítems, los varones ingieren más verduras (p< 0.036) y desayunan lácteos (p< 0.043) mientras que las mujeres hacen un mayor uso del aceite de oliva (p< 0.028). Aunque a nivel global los escolares obtienen valores más elevados de adherencia a una DM alta (p< 0.013), solo el 38.8% escolares presentan una elevada adherencia a la DM, siendo Primaria con mayor adherencia a la DM alta (p< 0.001). Conclusiones: el sexo no es un elemento diferenciador en la calidad de la DM. Se observa un descenso progresivo en los niveles óptimos de DM a partir de Primaria. Estos resultados sugieren la necesidad de implementación de actividades tendientes a la promoción de habilidades y actitudes que supongan la adherencia hacia hábitos alimenticios saludables.

ABSTRACT The Mediterranean diet is considered one of the healthiest dietary models. The objective of this study was to analyse the degree of adherence to the Mediterranean diet (MD) in schoolchildren according to sex and educational stage. A cross-sectional descriptive study was carried out (n= 634, 280 men and 354 women). Adherence to MD was measured using the KIDMED questionnaire. Adherence to the quality of MD did not differ significantly between men and women. However, according to the items, men ingested more fresh vegetables (p< 0.036) and consumed a dairy breakfast (p< 0.043) while women used olive oil more often (p< 0.028). Although, on a global level, the students obtained high values of adherence to a MD (p< 0.013), only 38.8% of the students had high adherence to MD, with Primary Education being the stage with the highest adherence to MD (p< 0.001). Conclusions: Sex was not a differentiating factor to the quality of MD. There is a progressive decrease in the optimal levels of MD from primary education. These results suggest the need to implement activities aimed at the promotion of skills and attitudes that improve adherence to healthy eating habits.

Neofobia alimentaria y trastornos de conducta alimentaria: Impacto en la adherencia a la dieta mediterránea de universitarios españoles / Food neophobia and eating disorders: Impact on adherence to the Mediterranean diet of Spanish university students

RESUMEN Este estudio evaluó la actitud de los universitarios murcianos hacia los nuevos alimentos y su relación con la adherencia a la dieta mediterránea, el riesgo de alteraciones de la conducta alimentaria y su asociación con la masa corporal. Participaron estudiantes de la Universidad de Murcia a los cuales se realizaron mediciones antropométricas, peso y talla, para estimar el índice de masa corporal y se estableció su condición nutricional, y se aplicaron las encuestas para identificación de trastornos de conducta alimentaria y neofobia alimentaria. Participaron un total de 300 universitarios con un promedio de edad de 21.3 años. Sólo el 14% de las mujeres y 35% de los hombres presentaron exceso de peso. Un 44% presentan buena adherencia a la dieta mediterránea. La Neofobia fue ligeramente mayor en mujeres que en hombres. Entre los resultados se identificó que existen más conductas de trastornos de conducta alimentaria (15.5%) que neofobia (11.5%), impactando negativamente a la adherencia a la dieta mediterránea. Los universitarios de la Región de Murcia, presentan una puntuación en trastorno de la conducta alimentaria inferior a la reportada por otros autores, no existiendo diferencias significativas entre esta y el sexo, la adherencia a la dieta mediterránea o el IMC.

ABSTRACT The study was designed to evaluate the attitude of Spanish undergraduates towards new foods and its impact on adherence to the Mediterranean diet, risk of altered eating behavior and its association with body mass. Undergraduates of the University of Murcia were invited to participate. Anthropometry (weight and height) was measured to estimate body mass and nutritional status and surveys were administered to identify eating disorders and food neophobia. A total of 300 undergraduates participated, with a mean age of 21.3 years. Only 14% of the women and 35% of the men were overweight; 44% had good adherence to the Mediterranean diet. Neophobia is slightly higher in females than males. We observed more eating disorder behaviors (15.5%) compared to food neophobia (11.5%) and that both negatively impacted the adherence to the Mediterranean diet. Undergraduates from the Murcia Region, reported an eating disorder values lower than that reported by other authors. No significant differences were found between this and sex, adherence to the Mediterranean diet or BMI.